CD86 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD86 |
| Clone | GL-1 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µg |
| Concentration | 0.5mg/mL |
| Applications | Flow Cytometry, Immunohistochemistry, IF Microscopy |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD86 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD86. Cross reactivity with CD86 from other sources has not been tested. Anti-CD86 is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. Anti-CD86 reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells. |
| Immunogen | Anti-CD86 Antibody (Monoclonal) was produced by repeated immunizations with CD86 antigen. |
| Other Names | T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1, CD86, Cd86 |
| Gene, Accession # | Cd86, Gene ID: 12524, NCBI: NP_062261.3, UniProt: P42082 |
| Catalog # | 200-502-N90 |
| Price | $459 |
| Order / More Info | CD86 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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