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Antigenic Specificity | Huntington phospho S434 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified, no preservative |
Size | 100 µg |
Concentration | 1.07 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Huntingtin pS434 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of the S434 residue. A BLAST analysis was used to suggest cross-reactivity with human and mouse based on 100% sequence homology. Cross-reactivity with Huntington pS434 from other sources has not been determined. Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington's disease protein is ~350kD in size and is localized in the brain. Anti-Huntington antibody is ideal for investigators interested in Neuroscience research. |
Immunogen | Anti-Huntingtin pS434 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Huntington disease protein. |
Other Names | rabbit anti-Huntington pS434 antibody, rabbit anti-Huntingtin pS434 antibody, HD protein, HTT, Huntington Disease Protein, Huntington disease, IT15, LOMARS |
Gene, Accession # | HTT, Gene ID: 3064, NCBI: NP_002102.4, UniProt: P42858 |
Catalog # | 600-401-J82 |
Price | $475 |
Order / More Info | Huntington phospho S434 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |