PD-1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | PD-1 |
| Clone | 7A11B1 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-PD-1 Monoclonal Antibody was Protein A purified. Cross reactivity with PD-1 [7A11B1] from other sources has not been determined. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE. |
| Immunogen | Anti-PD-1 antibody was produced in mice by repeated immunizations with a ~150 amino acid recombinant protein from near the N-terminus of mouse PD-1. |
| Other Names | PD-1 Antibody [7A11B1] , PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1 |
| Gene, Accession # | PDCD1, Gene ID: 5133, NCBI: Q15116, UniProt: Q15116 |
| Catalog # | 200-301-DK3 |
| Price | $485 |
| Order / More Info | PD-1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
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