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Antigenic Specificity | RING1B |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse, chinese hamster |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity purified Anti-RING1B antibody is directed against human RING1B protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, chimpanzee, orangutan, mouse, rat, dog, bovine, frog and chicken based on 100% homology for the immunogen sequence. Expect cross reactivity with RING1B from zebrafish, as only a single amino acid residue changes within the immunogen sequence (92% positive by BLAST). Cross reactivity with RING1B homologues from other sources has not been determined. RING1B (also known as BAP1 and RNF2) is one of the PcG proteins. The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity. Anti-RINGB1 Antibody is useful for researchers interested in epigenetics, ubiquitin, and transcription factor research. |
Immunogen | RING1B Antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 180-205 of human RING1B protein. |
Other Names | goat anti-RING1B Antibody, RING finger protein BAP1 antibody, DING antibody, RING finger protein 1B, E3 ubiquitin protein ligase RING 2 antibody, Huntingtin interacting protein 2 interacting protein 3 antibody, Anti-RNF2 antibody, HIP2-interacting protein 3, Protein DinG |
Gene, Accession # | RNF2, Gene ID: 6045, NCBI: 6005747, UniProt: Q99496 |
Catalog # | 600-101-292 |
Price | $475 |
Order / More Info | RING1B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |