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Antigenic Specificity | Esterase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | porcine |
Isotype | n/a |
Format | serum |
Size | 2 mL |
Concentration | 85 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-rabbit serum, purified and partially purified Esterase [Porcine Liver]. Cross reactivity against Esterase from other tissues and species may occur but have not been specifically determined. Esterase is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. It is active towards triacylglycerides containing short-chain fatty acids from C2 to C6, and 13-monoacylglycerols containing fatty acids from C2 to C12; and inactive on long-chain triacylglycerols and diacylglycerol. it hydrolyzes aromatic and alkyl esters and vitamin A acetate. The hydrolysis rate depends upon the amino acid promoiety and the esterification site of the prodrug. Aromatic promoieties are favored, highest rates are observed with phenylalanyl progdrugs, hydrolysis of valyl and isoleucyl prodrugs is less efficient. With floxuridine prodrugs, activity is higher on 5' monoesters than on 3' monoesters; while with gemcitabine prodrugs, activity is higher on 3' monoesters than on 5' monoesters. |
Immunogen | Esterase [Porcine Liver] |
Other Names | rabbit anti-Esterase Antibody, Liver carboxylesterase, Proline-beta-naphthylamidase, Retinyl ester hydrolase |
Gene, Accession # | CES3, Gene ID: 100626873, NCBI: 343791015, UniProt: Q29550 |
Catalog # | 100-4169 |
Price | $1225 |
Order / More Info | Esterase Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |