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Antigenic Specificity | NIK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NIK Antibody is affinity chromatography purified via peptide column. Cross reactivity with NIK from other sources has not been determined. Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, LPS and mitogens. A serine/threonine protein kinase which mediates NF-kB activation by IL-1, TNFa and CD95 was identified recently and designated NIK (for NF-kB inducing kinase). NIK is an activator of IkB kinase alpha and beta (IKKa and IKKb). Therefore, NIK is a key molecule in the NF-kB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products. |
Immunogen | Anti-NIK antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human NIK. |
Other Names | NIK Antibody, HS, NIK, HSNIK, FTDCR1B, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, HsNIK |
Gene, Accession # | MAP3K14, Gene ID: 9020, NCBI: Q99558, UniProt: Q99558 |
Catalog # | 200-401-DB3 |
Price | $475 |
Order / More Info | NIK Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |