NIK Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityNIK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA
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DescriptionAnti-NIK Antibody is affinity chromatography purified via peptide column. Cross reactivity with NIK from other sources has not been determined. Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, LPS and mitogens. A serine/threonine protein kinase which mediates NF-kB activation by IL-1, TNFa and CD95 was identified recently and designated NIK (for NF-kB inducing kinase). NIK is an activator of IkB kinase alpha and beta (IKKa and IKKb). Therefore, NIK is a key molecule in the NF-kB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.
ImmunogenAnti-NIK antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human NIK.
Other NamesNIK Antibody, HS, NIK, HSNIK, FTDCR1B, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, HsNIK
Gene, Accession #MAP3K14, Gene ID: 9020, NCBI: Q99558, UniProt: Q99558
Catalog #200-401-DB3
Price$475
Order / More InfoNIK Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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