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Antigenic Specificity | CDC42 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CDC42 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with CDC42 from other sources has not been determined. CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist. |
Immunogen | Anti-CDC42 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human CDC42. |
Other Names | CDC42 Antibody, G25K, CDC42Hs, Cell division control protein 42 homolog, G25K GTP-binding protein |
Gene, Accession # | CDC42, Gene ID: 998, NCBI: NP_001782, UniProt: P60953 |
Catalog # | 200-901-AJ3 |
Price | $475 |
Order / More Info | CDC42 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |