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Antigenic Specificity | Cdk5 |
Clone | 1H3 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µL |
Concentration | 10 mini blots |
Applications | Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CDK5 Antibody is directed against rat CDK5 protein. The antibody was Protein G purified from cell culture supernatant by chromatography. The antibody shows no cross reactivity with the Cdk5 cofactor p35 or its degradation product p25. Reactivity is reported to occur from human and mouse. Cross-reactivity with CDK5 from other species has not been determined. CDK5 antibody recognizes the neuronal protein kinase Cdk5 which is implicated in a vast array of normal neuronal functions including regulation of neurotransmitter synthesis, the presynaptic vesicle cycle, neurotransmitter receptor trafficking and dopamine neurotransmission. At the same time Cdk5 has been implicated in a plethora of neurological and neuropsychiatric disorders including Alzheimer's, Parkinson's, Huntington's, epilepsy, schizophrenia, and drug addiction. Detection of Cdk5 in normal samples as well as tissue undergoing neurodegeneration may advance studies in these areas. Moreover, this antibody may allow more accurate postmortem evaluations of Cdk5 protein expression, and thus serve as a valuable new reagent for neuropathology. Anti-CDK5 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-CDK5 Antibody was produced by repeated immunizations with purified rat Cdk5 |
Other Names | mouse anti-cdk5 antibody, cdk, mouse anti-Cyclin-dependent kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit |
Gene, Accession # | Cdk5, Gene ID: 140908, UniProt: Q03114 |
Catalog # | 200-301-163 |
Price | $485 |
Order / More Info | Cdk5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 34862365 |