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Antigenic Specificity | CD45 |
Clone | HI30 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | allophycocyanin (APC) conjugate |
Size | 500 µL |
Concentration | 0.025 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Allophycocyanin conjugated CD45 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD45. Reactivity is observed against human CD45. Cross reactivity is observed with Chimpanzee. Reactivity with CD45 from other sources has not been tested. Anti-CD45 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells. |
Immunogen | Anti-CD45 Antibody (Monoclonal) was produced by repeated immunizations with CD45 antigen. |
Other Names | Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, CD45, PTPRC |
Gene, Accession # | PTPRC, Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
Catalog # | 200-326-N68 |
Price | $399 |
Order / More Info | CD45 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |