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Antigenic Specificity | Paralemmin3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Paralemmin3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform. Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway. |
Immunogen | Anti-Paralemmin3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human Paralemmin3. |
Other Names | Paralemmin3 Antibody, Paralemmin-3 |
Gene, Accession # | PALM3, Gene ID: 342979, NCBI: NP_001138500, UniProt: A6NDB9 |
Catalog # | 600-401-DJ8 |
Price | $475 |
Order / More Info | Paralemmin3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |