STAT1 alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySTAT1 alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatDEAE purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-STAT1 alpha Antibody is purified by DEAE purification methods. No reaction to the 84 kDa STAT1a. STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-a, IFN-b, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). STAT1 has two forms, the 91 kDa STAT1a and the 84 kDa STAT1b which are encoded by the same gene with splicing variant.
ImmunogenAnti-STAT1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the C-terminus of human STAT1 alpha. The sequences differ from the murine corresponding sequences by four amino acids.
Other NamesSTAT1 alpha Antibody, CANDF7, ISGF-3, STAT91
Gene, Accession #STAT1, Gene ID: 6772, NCBI: NP_009330.1, UniProt: P42224
Catalog #200-401-EV3
Price$475
Order / More InfoSTAT1 alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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