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Antigenic Specificity | CARM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CARM1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CARM1 from other sources has not been determined. Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription. |
Immunogen | Anti- CARM1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the N-terminus of human CARM1. |
Other Names | CARM1 Antibody, PRMT4, PRMT4, Histone-arginine methyltransferase CARM1, Coactivator-associated arginine methyltransferase 1 |
Gene, Accession # | CARM1, Gene ID: 10498, NCBI: NP_954592, UniProt: Q86X55 |
Catalog # | 600-401-AB7 |
Price | $475 |
Order / More Info | CARM1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |