AFAP1L Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityAFAP1L
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-AFAP1L Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members. The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation (1, 4). Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.
ImmunogenAnti-AFAP1L1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminus of human AFAP1L1.
Other NamesAFAP1L Antibody, Actin filament-associated protein 1-like 1, AFAP1-like protein 1
Gene, Accession #AFAP1L1, Gene ID: 134265, NCBI: NP_689619, UniProt: Q8TED9
Catalog #600-401-X78
Price$475
Order / More InfoAFAP1L Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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