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Antigenic Specificity | CARD8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CARD8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CARD8 from other sources has not been determined. Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo-ICE. Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein, it has been suggested that it functions as an adaptor molecule regulating caspase-1 and NF-kB activation. |
Immunogen | Anti-CARD8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids at the C-terminus of human CARD8. |
Other Names | CARD8 Antibody, NDPP, DACAR, DAKAR, NDPP1, TUCAN, CARDINAL, KIAA0955, Caspase recruitment domain-containing protein 8, Apoptotic protein NDPP1 |
Gene, Accession # | CARD8, Gene ID: 22900, NCBI: AAG50014, UniProt: Q9Y2G2 |
Catalog # | 600-401-AB5 |
Price | $475 |
Order / More Info | CARD8 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |