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Antigenic Specificity | CTRP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CTRP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size. Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice. |
Immunogen | Anti-CTRP1 (IN) antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the internal region of human CTRP1. |
Other Names | CTRP1 Antibody, GIP, CTRP1, ZSIG37, UNQ310/PRO353, Complement C1q tumor necrosis factor-related protein 1, G protein-coupled receptor-interacting protein, GIP |
Gene, Accession # | C1QTNF1, Gene ID: 114897, NCBI: NP_940995, UniProt: Q9BXJ1 |
Catalog # | 600-401-AP4 |
Price | $475 |
Order / More Info | CTRP1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |