Edit |   |
---|---|
Antigenic Specificity | CD14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 0.5 mg/mL |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CD14 antibody is directed against mouse CD14 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from mouse based on 100% homology for the immunogen sequence. Cross reactivity with CD14 from other sources has not been determined. CD14, Cluster of differentiation 14, single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. By in situ hybridization and study of somatic cell hybrid DNA that the gene is located at bands 5q23-q31. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. This antibody is suitable for researchers interested in stem cell research. |
Immunogen | CD14 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse CD14. |
Other Names | Myeloid cell-specific leucine-rich glycoprotein, CD_antigen=CD14 |
Gene, Accession # | Cd14, Gene ID: 12475, NCBI: NP_033971.1, UniProt: P10810 |
Catalog # | 600-401-R04 |
Price | $445 |
Order / More Info | CD14 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |