Edit |   |
Antigenic Specificity | Neurofilament M |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat, bovine, chicken |
Isotype | n/a |
Format | IgY fraction |
Size | 100 µL |
Concentration | Titrated value sufficient to run approximately 10 mini blots. |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NF-M antibody is directed against NF-M protein. The antibody is a total IgY fraction. Expect reactivity with the following species based on sequence homology: chicken, human, mouse. Cross reactivity with NF-M from other species has not been determined. NF-M antibody detects Neurofilament M protein. Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease. Neurofilament M Antibody is ideal for investigators involved in Cell Signaling and Neuroscience research. |
Immunogen | Anti-NF-M Monoclonal Antibody was produced by repeated immunizations with recombinant C-terminus part of NF-M expressed in E. coli. |
Other Names | chicken anti-Neurofilament M antibody, Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein |
Gene, Accession # | Nefm, Gene ID: 24588, UniProt: P12839 |
Catalog # | 212-901-D84 |
Price | $475 |
Order / More Info | Neurofilament M Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 23345206 // 30320556 // 30463006 // 32859714 |