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Antigenic Specificity | DUX4 |
Clone | P2B1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-DUX4 Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human DUX4 protein. A BLAST analysis was used to suggest cross-reactivity with DUX4 from human based on 100% homology with the immunizing sequence. It does not cross react with DUX4c. Cross-reactivity with DUX4 from other sources has not been determined. Transcription Factor research. DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues. |
Immunogen | DUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein. |
Other Names | mouse anti-DUX4 Antibody, Double homeobox protein 4, Double homeobox protein 10, DUX4, DUX10 |
Gene, Accession # | DUX4, Gene ID: 100288687, NCBI: NP_001280727.1, UniProt: Q9UBX2 |
Catalog # | 209-301-F23 |
Price | $485 |
Order / More Info | DUX4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |