DUX4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityDUX4
CloneP2B1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size100 µg
Concentration1mg/mL
ApplicationsImmunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-DUX4 Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human DUX4 protein. A BLAST analysis was used to suggest cross-reactivity with DUX4 from human based on 100% homology with the immunizing sequence. It does not cross react with DUX4c. Cross-reactivity with DUX4 from other sources has not been determined. Transcription Factor research. DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
ImmunogenDUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein.
Other Namesmouse anti-DUX4 Antibody, Double homeobox protein 4, Double homeobox protein 10, DUX4, DUX10
Gene, Accession #DUX4, Gene ID: 100288687, NCBI: NP_001280727.1, UniProt: Q9UBX2
Catalog #209-301-F23
Price$485
Order / More InfoDUX4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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