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Antigenic Specificity | DAPK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-DAPK2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. DAPK2 has no cross responses to DAPK1. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFN-gamma induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1. Ectopic expression of DAPK2 induced apoptosis in various types of cells. DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues. |
Immunogen | Anti-DAPK2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the C-terminus of human DAPK2. The sequence of. This antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2). |
Other Names | DAPK2 Antibody, DRP1, DRP-1, Death-associated protein kinase 2, DAP-kinase-related protein 1, DAP kinase 2 |
Gene, Accession # | DAPK2, Gene ID: 23604, NCBI: BAA88063, UniProt: Q9UIK4 |
Catalog # | 600-401-AS5 |
Price | $475 |
Order / More Info | DAPK2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |