WAC Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | WAC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-WAC Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of WAC are known to exist; this antibody will detect the larger isoform. The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress. |
| Immunogen | Anti-WAC antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the internal region of human WAC. |
| Other Names | WAC Antibody, Wwp4, BM-016, PRO1741, KIAA1844, WW domain-containing adapter protein with coiled-coil |
| Gene, Accession # | WAC, Gene ID: 51322, NCBI: NP_057712.2, UniProt: Q9BTA9 |
| Catalog # | 600-401-FX6 |
| Price | $475 |
| Order / More Info | WAC Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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