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Antigenic Specificity | IEX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IEX-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with IEX-1 from other sources has not been determined. IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression. |
Immunogen | Anti-IEX1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 24 amino acid synthetic peptide near the internal region of human IEX1. |
Other Names | IEX-1 Antibody, DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, DIF2, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2 |
Gene, Accession # | IER3, Gene ID: 8870, NCBI: NP_003888.2, UniProt: P46695 |
Catalog # | 600-401-BT1 |
Price | $475 |
Order / More Info | IEX1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |