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Antigenic Specificity | WIZ |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-WIZ Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least four isoforms of WIZ are known to exist; this antibody will detect all four. WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing. |
Immunogen | Anti-WIZ antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human TFF3. |
Other Names | WIZ Antibody, ZNF803, ZNF803, Protein Wiz, Widely-interspaced zinc finger-containing protein |
Gene, Accession # | WIZ, Gene ID: 58525, NCBI: NP_001317324.1, UniProt: O95785 |
Catalog # | 600-401-FZ2 |
Price | $475 |
Order / More Info | WIZ Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |