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Antigenic Specificity | Frequenin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 2.0 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was prepared from monospecific antiserum by immunoaffinity chromatography using Frequenin (recombinant) coupled to agarose beads. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Frequenin, or Neuronal calcium sensor, is a regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. It directly regulates GRK1 (RHOK), but not GRK2 to GRK5. It can substitute for calmodulin and it stimulates PI4KB kinase activity. It is involved in long-term synaptic plasticity through its interaction with PICK1. Ncs1 may also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel. |
Immunogen | Frequenin (recombinant from Mouse with extensive post-translational modifications) |
Other Names | rabbit anti-FREQUENIN antibody, NCS-1, FLUP, FREQ, Neuronal calcium sensor 1, frequenin homolog antibody, Frequenin-like protein antibody, NCS 1 antibody, NCS1 antibody |
Gene, Accession # | Ncs1, Gene ID: 14299, NCBI: NP_062655.1, UniProt: Q8BNY6 |
Catalog # | 600-401-216 |
Price | $475 |
Order / More Info | Frequenin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 12351722 |