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Antigenic Specificity | TLR7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TLR7 Antibody was purified from monospecific antiserum. This product is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross-reactivity with TLR7 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TLR7 from other sources has not been determined. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFN? secretion, suggesting the importance of TLR7 in virus recognition. Anti-TLR7 antibody is ideal for investigators involved in kinases, phosphatase, cytokines, growth factors and transcription factor research. |
Immunogen | TLR7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to an internal region of mouse TLR7. |
Other Names | PRO285 antibody, Toll like receptor 7 antibody, UNQ248 antibody |
Gene, Accession # | Tlr7, Gene ID: 170743, NCBI: 18875360, UniProt: P58681 |
Catalog # | 200-401-A64 |
Price | $475 |
Order / More Info | TLR7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 29954626 |