Slc35D1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Slc35D1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Slc35D1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is predicted to not cross-react with the highly homologous Slc35D2. The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia. |
| Immunogen | Anti-Slc35D1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide near the C-terminus of the human Slc35D1. |
| Other Names | Slc35D1 Antibody, UGTREL7, KIAA0260, UGTREL7, Solute carrier family 35 member D1, UGTrel7 |
| Gene, Accession # | SLC35D1, Gene ID: 23169, NCBI: NP_055954, UniProt: Q9NTN3 |
| Catalog # | 600-401-EP2 |
| Price | $475 |
| Order / More Info | Slc35D1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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