NMDA NR2B Subunit phospho Y1336 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NMDA NR2B Subunit phospho Y1336 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NMDA NR2B Subunit pY1336 antibody is directed against rat NMDA 2B receptor protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-NMDA NR2B Subunit pY1336 antibody is specific for the phosphorylated protein. Immunolabeling of the NMDAR NR2B subunit band is blocked by lambda-phosphatase treatment. The antibody has been directly tested for reactivity in Western blots rat tissue. Reactivity is expected from the following species based on 100% sequence homology: human, mouse and non-human primates. NMDA 2B pY1336 antibody detects NMDA 2B receptor protein. The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Phosphorylation of Tyr1336 is thought to potentiate NMDA receptor-dependent influx of calcium and ischemia may also increase the phosphorylation of this site. NMDA NR2B Subunit pY1336 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research. |
| Immunogen | Anti-NMDA NR2B Subunit pY1336 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1336. |
| Other Names | Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b |
| Gene, Accession # | Grin2b, Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
| Catalog # | 612-401-C88 |
| Price | $475 |
| Order / More Info | NMDA NR2B Subunit phospho Y1336 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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