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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | Flow Cytometry, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TLR4 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with TRL 4 from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TRL4 from other sources has not been determined. Cell Signaling research. The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling. The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa. |
Immunogen | TRL4 Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against synthetic peptide corresponding to an internal region of human TLR4. |
Other Names | ARMD10, CD284, TLR 4, TOLL, Toll like receptor 4 |
Gene, Accession # | TLR4, Gene ID: 7099, NCBI: NP_612564.1, UniProt: O00206 |
Catalog # | 600-401-G52 |
Price | $445 |
Order / More Info | TLR4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |