Synaptotagmin phospho S309 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySynaptotagmin phospho S309
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatimmunoaffinity purified
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry, Western Blot
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DescriptionAnti-Synaptotagmin 1 pS309 Antibody is directed against rat Synaptotagmin 1 phosphorylated at pS309. Synaptotagmin antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, chicken, human, mouse, non-human primate and zebra fish. Cross-reactivity with from other species has not been determined. Synaptotagmin 1 pS309 Antibody detects Synaptotagmin 1, which is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS. It is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Recent studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion. It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission. Anti-Synaptotagmin 1 pS309 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
ImmunogenAnti-Synaptotagmin pS309 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser309 of Synaptotagmin.
Other NamesSynaptotagmin-1, Synaptotagmin I, SytI, p65, Syt1
Gene, Accession #Syt1, Gene ID: 25716, UniProt: P21707
Catalog #612-401-E39
Price$475
Order / More InfoSynaptotagmin phospho S309 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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