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Antigenic Specificity | Hsp40 (YDJ1) |
Clone | 1G10.H8 |
Host Species | Mouse |
Reactive Species | yeast |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Hsp40, YDJ1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Hsp40 from yeast based on 100% homology with the immunizing sequence. Cross-reactivity with Hsp40 from other sources has not been determined. Heat Shock research. Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of Hsp40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not. Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. Hsp40 stimulates the ATPase activity of Hsp70 which in turn causes conformational changes of the unfolded proteins. The Hsp40-Hsp70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1. |
Immunogen | Hsp40 (YDJ1) Antibody was produced in mice by repeated immunizations raised against full length protein yeast Hsp40 (YDJ1). |
Other Names | Mitochondrial protein import protein MAS5, Yeast dnaJ protein 1, YDJ1, MAS5, YNL064C, N2418, YNL2418C |
Gene, Accession # | YDJ1, Gene ID: 855661, NCBI: NP_014335.1, UniProt: P25491 |
Catalog # | 200-301-E58 |
Price | $485 |
Order / More Info | Hsp40 (YDJ1) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |