SCARB1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySCARB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-SCARB1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SCARB1 from other sources has not been determined. Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.
ImmunogenAnti-SCARB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human SCARB1.
Other NamesSCARB1 Antibody, CLA1, SRB1, CLA-1, SR-BI, CD36L1, HDLQTL6, CLA1, Scavenger receptor class B member 1, CD36 and LIMPII analogous 1
Gene, Accession #SCARB1, Gene ID: 949, NCBI: Q8WTV0, UniProt: Q8WTV0
Catalog #600-401-EE0
Price$475
Order / More InfoSCARB1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific ReferencesPubMed: 30157426
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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