GOLPH1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-GOLPH1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GOLPH1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GOLPH1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with GOLPH1 from other sources has not been determined. GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymmetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression. |
| Immunogen | Anti-GOLPH1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the N-terminus of human GOLPH1. |
| Other Names | GOLPH1 Antibody, PAP7, GCP60, GOCAP1, GOLPH1, Golgi resident protein GCP60, Acyl-CoA-binding domain-containing protein 3 |
| Gene, Accession # | ACBD3, Gene ID: 64746, NCBI: EAW69775, UniProt: Q9H3P7 |
| Catalog # | 600-401-BM2 |
| Price | $475 |
| Order / More Info | GOLPH1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies