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Antigenic Specificity | SYTL5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SYTL5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members. SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis. |
Immunogen | Anti-SYTL5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human SYTL5. |
Other Names | SYTL5 Antibody, slp5, SLP5, Synaptotagmin-like protein 5 |
Gene, Accession # | SYTL5, Gene ID: 94122, NCBI: NP_001156806.1, UniProt: Q8TDW5 |
Catalog # | 600-401-EZ0 |
Price | $475 |
Order / More Info | SYTL5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |