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Antigenic Specificity | AQUAPORIN 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AQP2 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. AQP2 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with other members of the aquaporin protein family. Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorption. AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. |
Immunogen | Anti-AQP2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human AQP2. |
Other Names | AQP2 Antibody, AQP-CD, WCH-CD, Aquaporin-2, ADH water channel, AQP-2 |
Gene, Accession # | AQP2, Gene ID: 359, NCBI: NP_000477, UniProt: P41181 |
Catalog # | 600-401-Y54 |
Price | $475 |
Order / More Info | AQUAPORIN 2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |