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Antigenic Specificity | BCMA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-BCMA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with BCMA from other sources has not been determined. Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. |
Immunogen | Anti-BCMA antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide mapping at the C-terminus of human BCMA. |
Other Names | BCMA Antibody, BCM, BCMA, CD269, TNFRSF13A, BCM, Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein |
Gene, Accession # | TNFRSF17, Gene ID: 608, NCBI: NP_001183, UniProt: Q02223 |
Catalog # | 600-401-Z51 |
Price | $475 |
Order / More Info | BCMA Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |