KLF17 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityKLF17
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionAnti-KLF17 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist; this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins. KLF17, also known as ZNF393, is a member of the Sp/KLF family of transcription factors (1,2). KLF17 binds to the promoter and negatively regulates the transcription of Id-1, a key metastasis regulator in breast cancer (3). Suppression of KLF17 promotes breast cancer cell invasion and epithelial-mesenchymal transition (3). Down-regulated KLF17 expression is also associated tumor invasion and poor prognosis in hepatocellular carcinoma, suggesting that the level of KLF17 expression can serve as a prognostic indicator (4).
ImmunogenAnti-KLF17 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human KLF17.
Other NamesKruppel-like factor 17, zinc finger protein 393, ZNF393, Zfp393
Gene, Accession #KLF17, Gene ID: 128209, NCBI: NP_775755, UniProt: Q5JT82
Catalog #600-401-CE8
Price$475
Order / More InfoKLF17 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

Profile of ROCKLAND IMMUNOCHEMICALS INC.

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