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Antigenic Specificity | KLF17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KLF17 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist; this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins. KLF17, also known as ZNF393, is a member of the Sp/KLF family of transcription factors (1,2). KLF17 binds to the promoter and negatively regulates the transcription of Id-1, a key metastasis regulator in breast cancer (3). Suppression of KLF17 promotes breast cancer cell invasion and epithelial-mesenchymal transition (3). Down-regulated KLF17 expression is also associated tumor invasion and poor prognosis in hepatocellular carcinoma, suggesting that the level of KLF17 expression can serve as a prognostic indicator (4). |
Immunogen | Anti-KLF17 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human KLF17. |
Other Names | Kruppel-like factor 17, zinc finger protein 393, ZNF393, Zfp393 |
Gene, Accession # | KLF17, Gene ID: 128209, NCBI: NP_775755, UniProt: Q5JT82 |
Catalog # | 600-401-CE8 |
Price | $475 |
Order / More Info | KLF17 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |