Rabphilin 3A Phospho S234 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityRabphilin 3A Phospho S234
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatimmunoaffinity purified
Size100 µL
ConcentrationTitrated value sufficient to run approximately 10 mini blots.
ApplicationsImmunohistochemistry, Western Blot
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DescriptionAnti-Rabphilin 3A pS234 antibody is directed against rat rabphilin 3A protein phosphorylated at serine 234. Rabphilin 3A pS234 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. The immunolabeling of the rabphilin band was completely blocked by the phosphopeptide used as antigen while the dephosphopeptide had no effect on the immunolabeling. Cross reactivity with Rab 3A from other species has not been determined, however, the sequence of the immunogen shows 100% identity to mouse, therefore, cross reactivity is expected. Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes. The expression of rabphilin 3A is reduced in an animal model of Huntington's disease. Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner. Anti-Rabphilin 3A antibody is ideal for investigators involved in Signal Transduction, Cell Signaling, and Neuroscience research.
ImmunogenAnti-Rabphilin 3A pS234 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH.
Other NamesRabphilin 3A Homolog, Rabphilin-3A, RP3A, Rph3A, Exophilin 1, Exophilin-1
Gene, Accession #Rph3a, Gene ID: 171039, UniProt: P47709
Catalog #612-401-E22
Price$475
Order / More InfoRabphilin 3A Phospho S234 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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