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Antigenic Specificity | Caveolin-1 phospho S168 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Caveolin-1 pS168 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of human S168 residue. A BLAST analysis was used to suggest cross-reactivity with primate, human, horse, cat, and dog based on 100% sequence homology. Cross-reactivity with Caveolin-1 pS168 from other sources has not been determined. Caveolin 1 is a ubiquitous protein found within the membranes of caveolea, theoretically acting as a scaffolding protein. Direct interaction with G-protein alpha subunits allows regulation of their activity. A regulatory protein, it is involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, and is also a factor in the regulation of CTNNB1-mediated signaling through the Wnt pathway. Expressed in the muscle and lung tissues predominantly, defects in CAV1 is the cause of congenital generalized lipodystrophy type 3, or autosomal recessive disorders such as adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset diabetes. Anti-Caveolin 1 antibody is ideal for researchers in Metabolism, Cancer, Signal Transduction, and Cardiovascular research. |
Immunogen | Anti-Caveolin 1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Caveolin-1 protein. |
Other Names | rabbit anti-Caveolin-1 pS168 Antibody, CAV1, CAV, CAV 1, rabbit anti-Caveolin 1 pS168 Antibody, Caveolin1 |
Gene, Accession # | CAV1 UniProt: Q03135 |
Catalog # | 600-401-J64 |
Price | $475 |
Order / More Info | Caveolin-1 phospho S168 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |