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Antigenic Specificity | Rab3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Rab 3 antibodies was affinity purified from monospecific antiserum by immunoaffinity purification. This antibody is directed against rat Rab3 proteins. Cross reactivity with Rab 3 from other species has not been determined, however, the sequence of the immunogen shows 100% identity to human, mouse, Xenopus and non-human primates, therefore cross reactivity is expected. Rab 3 Antibody detects Rab 3 which belongs to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab3's are thought to play a key role in presynaptic vesicle trafficking and priming. |
Immunogen | Anti-Rab 3 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH. |
Other Names | Ras-related protein Rab-3A, Rab3a |
Gene, Accession # | Rab3a, Gene ID: 25531, NCBI: NP_037150.2, UniProt: P63012 |
Catalog # | 612-401-E20 |
Price | $475 |
Order / More Info | Rab3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |