IKB alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityIKB alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatserum
Size100 µL
Concentration80 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionIKB alpha Antibody was prepared from monospecific antiserum by delipidation and defibrination. Anti- IkBa may react non-specifically with other proteins. Control peptide (code #100-4167P) will compete only with the specific reaction of antiserum with IkBa. Anti-IKB alpha Antibody detects IkBa. I-kappa-B-alpha inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, IKBA becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. Anti-IKBa Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction and Immunology research.
ImmunogenIKB alpha Antibody was produced by repeated immunizations with a synthetic IkBa peptide corresponding to a region near the C-terminus of the human protein.
Other Namesrabbit anti-IKB alpha Antibody, IkappaBalpha antibody, IKBA antibody, IKBalpha antibody, MAD3 antibody, NF kappa B inhibitor alpha antibody, NFKBI antibody, NFKBIA antibody
Gene, Accession #NFKBIA, Gene ID: 4792, NCBI: CAB65556.2, UniProt: P25963
Catalog #100-4167C
Price$475
Order / More InfoIKB alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific ReferencesPubMed: 9343439 // 9566902 // 9988719 // 12648451
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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