NUP107 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityNUP107
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-NUP107 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NUP107 from other sources has not been determined. The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
ImmunogenAnti-NUP107 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide from near the internal region of human NUP107.
Other NamesNUP107 Antibody, NUP84, Nuclear pore complex protein Nup107, 107 kDa nucleoporin
Gene, Accession #NUP107, Gene ID: 57122, NCBI: P57740, UniProt: P57740
Catalog #600-401-DF2
Price$475
Order / More InfoNUP107 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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