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Antigenic Specificity | NMDAR2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 0.5 mg/mL |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NMDAR2B antibody is directed against human NMDAR2B protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on 100% homology for the immunogen sequence. Cross reactivity with NMDAR2B from other sources has not been determined. The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B (NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz. This antibody is suitable for researchers interested in neuroscience research. |
Immunogen | NMDAR2B affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human NMDAR2B. |
Other Names | Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B, |
Gene, Accession # | GRIN2B, Gene ID: 2904, NCBI: NP_000825.2, UniProt: Q13224 |
Catalog # | 600-401-P64 |
Price | $445 |
Order / More Info | NMDAR2B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |