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Antigenic Specificity | Catenin gamma (Plakoglobin) |
Clone | 15F11 |
Host Species | Mouse |
Reactive Species | human, bovine |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg |
Concentration | 100µg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Catenin gamma (Plakoglobin) antibody was purified from mouse ascites by protein A chromatography. This product reacts with human and bovine. Cross reactivity with Catenin gamma from other sources has not been determined. Junction Plakoglobin (JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. This antibody is suitable for researchers interested in cell adhesion and cancer research. |
Immunogen | Catenin gamma (Plakoglobin) antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to chicken plakoglobin. |
Other Names | DP3, PDGB, PKGB, CTNNG, DPIII, ARVD12, Catenin gamma, Desmoplakin III, Desmoplakin-3 |
Gene, Accession # | JUP, Gene ID: 3728, NCBI: NP_002221.1, UniProt: P14923 |
Catalog # | 200-301-P27 |
Price | $485 |
Order / More Info | Catenin gamma (Plakoglobin) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |