Bst2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Bst2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Bst2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bst2 from other sources has not been determined. Bst2 was first identified as a novel terminal B-cell-restricted antigen termed HM1.24 that is expressed on certain bone marrow cells as well as other tissues. The surface expression of Bst2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line, suggesting that this protein is involved in pre-B-cell growth. Later experiments also showed it to be upregulated in several myeloma cells. More recently, Bst2 was identified an inhibitor of retroviral release from human cells whose activity is antagonized by the HIV-1 accessory protein Vpu. While Bst2 caused retention of virions on cell surfaces or endocytosis into Bst2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release. This activity may represent a potential therapeutic strategy for the treatment of HIV/AIDS. |
| Immunogen | Anti-Bst2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide near the N-terminus of the mouse Bst2. |
| Other Names | Bst2 Antibody, GREG, Bst-2, CD317, C87040, DAMP-1, 2310015I10Rik, Bone marrow stromal antigen 2, BST-2 |
| Gene, Accession # | Bst2, Gene ID: 69550, NCBI: AAH87949, UniProt: Q8R2Q8 |
| Catalog # | 600-401-Z95 |
| Price | $475 |
| Order / More Info | Bst2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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