Tubulin beta 3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTubulin beta 3
CloneAA10
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG
FormatProtein G purified
Size100 µL
ConcentrationTitrated value sufficient to run approximately 10 mini blots.
ApplicationsImmunohistochemistry, Western Blot
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DescriptionAnti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein. The antibody was Protein G purified from cell culture supernatant. Cross reactivity with tubulin beta 3 from other species has not been determined. Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.
ImmunogenAnti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.
Other Namesmouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III
Gene, Accession #Tubb3, Gene ID: 246118, NCBI: AAM28438.1, UniProt: Q4QRB4
Catalog #212-301-E55
Price$475
Order / More InfoTubulin beta 3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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