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Antigenic Specificity | Tubulin beta 3 |
Clone | AA10 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG |
Format | Protein G purified |
Size | 100 µL |
Concentration | Titrated value sufficient to run approximately 10 mini blots. |
Applications | Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein. The antibody was Protein G purified from cell culture supernatant. Cross reactivity with tubulin beta 3 from other species has not been determined. Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy. |
Immunogen | Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin. |
Other Names | mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III |
Gene, Accession # | Tubb3, Gene ID: 246118, NCBI: AAM28438.1, UniProt: Q4QRB4 |
Catalog # | 212-301-E55 |
Price | $475 |
Order / More Info | Tubulin beta 3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |