Piccolo Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityPiccolo
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size100 µg
Concentration1mg/mL
ApplicationsIF Microscopy, Western Blot
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DescriptionAnti-Piccolo Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Piccolo from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. No cross-reactivity to Bassoon. Cross-reactivity with Picollo from other sources has not been determined. Neuroscience research. Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1.
ImmunogenPiccolo Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against full length protein.
Other NamesProtein piccolo, Aczonin, PCLO, ACZ, KIAA0559
Gene, Accession #PCLO, Gene ID: 27445, NCBI: NP_055325.2, UniProt: Q9Y6V0
Catalog #600-401-G30
Price$445
Order / More InfoPiccolo Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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