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Antigenic Specificity | Piccolo |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Piccolo Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Piccolo from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. No cross-reactivity to Bassoon. Cross-reactivity with Picollo from other sources has not been determined. Neuroscience research. Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1. |
Immunogen | Piccolo Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against full length protein. |
Other Names | Protein piccolo, Aczonin, PCLO, ACZ, KIAA0559 |
Gene, Accession # | PCLO, Gene ID: 27445, NCBI: NP_055325.2, UniProt: Q9Y6V0 |
Catalog # | 600-401-G30 |
Price | $445 |
Order / More Info | Piccolo Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |