PHC3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityPHC3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-PHC3 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. PHC3 antibody is human, mouse and rat specific. At least six isoforms of PHC3 are known to exist. Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4).
ImmunogenAnti-PHC3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the N-terminus of human PHC3.
Other NamesPHC3 Antibody, EDR3, HPH3, EDR3, PH3, Polyhomeotic-like protein 3, Early development regulatory protein 3, hPH3
Gene, Accession #PHC3, Gene ID: 80012, NCBI: NP_079223, UniProt: Q8NDX5
Catalog #600-401-DM0
Price$475
Order / More InfoPHC3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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