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Antigenic Specificity | PHC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-PHC3 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. PHC3 antibody is human, mouse and rat specific. At least six isoforms of PHC3 are known to exist. Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4). |
Immunogen | Anti-PHC3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the N-terminus of human PHC3. |
Other Names | PHC3 Antibody, EDR3, HPH3, EDR3, PH3, Polyhomeotic-like protein 3, Early development regulatory protein 3, hPH3 |
Gene, Accession # | PHC3, Gene ID: 80012, NCBI: NP_079223, UniProt: Q8NDX5 |
Catalog # | 600-401-DM0 |
Price | $475 |
Order / More Info | PHC3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |