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Antigenic Specificity | CXXC5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CXXC5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members. CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development. |
Immunogen | Anti-CXXC5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human CXXC5. |
Other Names | CXXC5 Antibody, CF5, WID, RINF, HSPC195, CXXC-type zinc finger protein 5, Putative MAPK-activating protein PM08, CF5 |
Gene, Accession # | CXXC5, Gene ID: 51523, NCBI: NP_057547, UniProt: Q7LFL8 |
Catalog # | 600-401-AR7 |
Price | $475 |
Order / More Info | CXXC5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |