Edit |   |
---|---|
Antigenic Specificity | RUSC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-RUSC2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms are known to exist; this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1. RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions. |
Immunogen | Anti-RUSC2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the C-terminus of human RUSC2. |
Other Names | RUSC2 Antibody, Iporin, KIAA0375, Iporin, Interacting protein of Rab1 |
Gene, Accession # | RUSC2, Gene ID: 9853, UniProt: Q8N2Y8 |
Catalog # | 600-401-ED1 |
Price | $475 |
Order / More Info | RUSC2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |