Integrin alpha 4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Integrin alpha 4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Integrin alpha 4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms are known to exist. The immunogen to this antibody is outside of the Integrin alpha4 recombinant protein fragment and thus will not recognize it. The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. |
| Immunogen | Anti-Integrin alpha 4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide from near the C-terminus of human Integrin alpha 4. |
| Other Names | Integrin alpha 4 Antibody, IA4, CD49D, Integrin alpha-4, CD49 antigen-like family member D |
| Gene, Accession # | ITGA4, Gene ID: 3676, NCBI: NP_000876, UniProt: P13612 |
| Catalog # | 600-401-BY3 |
| Price | $475 |
| Order / More Info | Integrin alpha 4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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