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Antigenic Specificity | KChlP2 K+ channel |
Clone | S60-73 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KChlP2 K+ channel Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with KChlP2 K+ channel from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with KChlP2 K+ channel from other sources has not been determined. Ion Channels research. There are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF handcontaining proteins required for the traffic of channel forming Kv4 K+ subunits to the plasma membrane. KChiP2 expression has been found to be significantly decreased in hypertrophy and heart failure, and does so thru modulatin of intracellular concentration and calcineurin/NFAT pathways. It has also been found that KChiP2 also functionally modulates the Cav1.2 governed Ltype calcium channel through a direct interaction between KChiP2 and the amino-terminus of Cav1.2. |
Immunogen | KChlP2 K+ channel Antibody was produced in mice by repeated immunizations raised against a fusion protein of full length of rat KChIP2b. |
Other Names | KCHIP2, Kv channel-interacting protein 2, A-type potassium channel modulatory protein 2, Potassium channel-interacting protein 2 |
Gene, Accession # | Kcnip2, Gene ID: 56817, NCBI: NP_001029133.1, UniProt: Q9JM59 |
Catalog # | 200-301-F80 |
Price | $485 |
Order / More Info | KChlP2 K+ channel Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |